Speaking of cholesterol, many people will immediately think that it will lead to the occurrence of some diseases, such as atherosclerosis, coronary heart disease and so on. But perhaps your understanding of cholesterol is only one-sided. This issue will share your knowledge of cholesterol from a scientific point of view, which may subvert your understanding of cholesterol.
Cholesterol is a lipid, a type of lipid compound. It is widely found in all animal tissues, especially in the brain and nervous tissue, and is also high in kidney, spleen, skin, liver and bile.
Cholesterol is an important part of the cell membrane, which can help the body synthesize vitamin D, generate bile, metabolize fat, synthesize sex hormones, etc.
Translation: Without cholesterol, there is no life. People who lack cholesterol will have metabolic disorders, calcium deficiency, abnormal physiological functions, and abnormal emotions.
Food-borne cholesterol has minimal effect on cholesterol in the body.
Cholesterol is mostly synthesized by the liver itself, and dietary intake of cholesterol has little effect on the total cholesterol level in the body. That is to say, generally speaking, the amount of cholesterol in your body is related to your genes, and to a certain extent, it is not directly related to whether you eat cholesterol foods or not. Experiments have shown that people with high cholesterol have little change in their cholesterol levels compared with a normal diet and a cholesterol-controlled diet (such as not eating egg yolks).
Strict control of fat intake increases cholesterol levels
Translation: Because the metabolism of cholesterol in the body must be combined with fatty acids, and fatty acids are obtained by eating meat and other substances, if you eat less fat, the cholesterol synthesized in the body cannot obtain more fatty acid metabolism, and it will be in the body. Accumulation, so some people who eat too light diets have increased cholesterol levels instead of falling.
Have the above three points subverted your understanding of cholesterol? With the improvement of living standards, the daily diet is also richer, and most people do not lack nutritional intake including fat and cholesterol. It is true that one’s own genes are the dominant factor, but uncontrolled diet and lack of physical exercise are also one of the important factors leading to the accumulation of cholesterol and fat in the body, and dyslipidemia is its pathological manifestation. Many people think that high blood fat = high cholesterol, but this understanding is inaccurate.
Dyslipidemia usually refers to an increase in plasma cholesterol and/or triglyceride, and also includes a decrease in high-density lipoprotein cholesterol. In other words, an increase in cholesterol, an increase in triglycerides (also called triglycerides), and a decrease in high-density lipoprotein, one of these three, can be confirmed as dyslipidemia.
Many hyperlipidemia patients have low cholesterol levels, but high levels of triglycerides, which also require active intervention. Triacylglycerol is synthesized by the body through the diet. When we eat food rich in fat, part of the fat is metabolized into energy for human life activities under the action of lipase, and for too much fat that is not needed temporarily, the body will synthesize triglycerol and store it in the body , you can simply understand it as the fat on your belly, or you can directly treat triglyceride as fat. Triglycerol is also an important cause of atherosclerosis, so it is very important to control the intake of fat in the daily diet
Low-density lipoprotein and high-density lipoprotein
Low-density lipoprotein cholesterol (LDL-C) is a major risk factor for the development and progression of atherosclerosis. A large amount of LDL enters the vascular wall through the vascular endothelium, and is eventually oxidized and phagocytosed to form foam cells. The foam cells continue to increase and fuse, forming the lipid core of atherosclerosis. The pathological essence of atherosclerosis is a chronic inflammatory response, and LDL is likely to be the initiation and maintenance factor of this chronic inflammatory response.
High-density lipoprotein (HDL) can transport cholesterol in peripheral tissues such as blood vessel walls to the liver for catabolism, which can reduce the deposition of cholesterol in blood vessel walls, thereby exerting an anti-atherosclerotic effect.
In short, low-density lipoprotein deposits on the walls of blood vessels and causes atherosclerosis, while high-density lipoproteins take cholesterol away from the blood vessel walls and send them to the liver for metabolism. So why do we hope that our low-density lipoprotein cholesterol should be as low as possible during the physical examination, and high-density lipoprotein cholesterol should preferably be higher.